Lipoprotein (a): a possible link between lipoprotein metabolism and thrombosis.
نویسندگان
چکیده
منابع مشابه
Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis.
Lipoprotein (a) [Lp(a)] has been associated with both anti-fibrinolytic and atherogenic effects. However, no direct link currently exists between this atherogenic lipoprotein and intravascular coagulation. The current study examined the binding and functional effects of Lp(a), its lipoprotein constituents, apoliprotein (a) [apo(a)] and low-density lipoprotein (LDL), and lysine-plasminogen (L-PL...
متن کاملEffect of adiposity on plasma lipid transfer protein activities: a possible link between insulin resistance and high density lipoprotein metabolism.
The mechanisms responsible for the decreased high density lipoprotein (HDL) cholesterol levels associated with obesity and insulin resistance are not well understood. Lecithin: cholesterol acyltransferase (LCAT) and cholesterol ester transfer protein (CETP) are key factors in the esterification of cholesterol in HDL and the subsequent transfer of cholesteryl ester towards apolipoprotein B-conta...
متن کاملFatty acid control of lipoprotein lipase: a link between energy metabolism and lipid transport.
Lipoprotein lipase (LPL) catalyzes the flux-generating step in transport of fatty acids from lipoprotein triacylglycerols into tissues for use in metabolic reactions. In vitro studies have shown that fatty acids can bind to the enzyme and impede its other interactions. In this study we have searched for evidence of fatty acid control of LPL in vivo by rapid infusion of a triacylglycerol emulsio...
متن کاملA Possible Link Between Smoking and Arterial Thrombosis
In a controlled, double blind study, the smoking of a single cigarette has been shown to increase the platelet's response to a standard aggregating stimulus. This phenomenon appears to be specifically related to the inhaling of tobacco smoke; it does not follow the smoking of lettuce leaf filled cigarettes. The platelet effect seems independent of the rise in plasma free fatty acids which follo...
متن کامل"lipoprotein (a) levels and coronary artery disease in iranian patients. is there a link?"
lipoprotein(a), an ldl variant, has been claimed to have a role in atherogenesis and therefore coronary artery disease (cad). however, its production and atherogenecity seems to vary among ethnic groups. in order to study the possible correlation between levels of lp(a) and cad in iranian patients who suffered myocardial infarction (mi), a case-control study was carried out on 120 mi patients a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Heart
سال: 1991
ISSN: 1355-6037
DOI: 10.1136/hrt.65.1.2